HUSAR Bioinformatics Lab
Deutsches Krebsforschungszentrum Department of Molecular Biophysics
Advanced Bioinformatics Workshop
 
Agenda
The aim of the advanced bioinformatics workshops is to bring you up to date with the different fields and latest developments in Bioinformatics. Exciting topics in Bioinformatics are reviewed. The advanced workshops (free of charge) discuss important programs and their underlying algorithms and include practical training sessions.

First Day

9:00 Introduction
9:10 Pairwise sequence alignment I

  • Principles of sequence comparison
  • Scoring Systems
  • Gap Penalties
  • Global Alignment
  • Local Alignment
9:45 Break
10:00 Pairwise sequence alignment II
  • Methods of sequence comparison
  • Window-based approaches
  • Dynamic programming-based approaches
  • Needleman-Wunsch / Smith-Waterman
10:45 Break
11:00 Multiple alignment
  • Approaches
  • Multidimensional dynamic programming
  • Progressive alignments
  • And others (DiAlign, Tcoffee, Muscle)
12:00 Lunch
14:00 Profiles and Hidden Markov Models in Biology
15:00 Break
15:15 Database searching I
  • FastA, Blast
16:00 Break
16:15 Database searching II
  • Strategies
  • Examples
17:00 End


Second Day

9:00 Exercises - PC-Room Main Building
11:00 Break
11:30 Promoter and gene prediction

  • Theoretical approaches to promoter and gene prediction
  • Examples and comparison of tools
12:30 Lunch
14:00 Functional analysis of proteins
  • - Motif searches
  • - Secondary structure prediction
  • - Tertiary structure and protein modelling
14:45 Break
15:00 Phylogeny I
15:45 Break
16:00 Phylogeny II 16:45 End

Register via the Mitarbeiterportal